Aconite – a Poison, or a Medicine? Ancient and Early Byzantine Testimonies
DOI:
https://doi.org/10.18778/2084-140X.12.24Keywords:
aconite, ancient medicine, Byzantine medicine, toxicology, Roman law, Byzantine lawAbstract
Aconite (Aconitum napellus) was one of the most notorious, poisonous plants in the ancient world. Its dangerous, lethal power – present in leaves, roots, stem, and tuber – was well known to the Greeks and the Romans from the earliest times. Evidence of this phenomenon is not only present in archaeological findings, but also in many writings – biographies, poems, legal codes, etc.
However, the most precise and detailed accounts come from treatises written by botanists, physicians and encyclopaedists, like Theophrastus, Nicander, Pliny the Elder, Dioscorides, or Galen, and by early Byzantine authors, Oribasius, Aetius of Amida, and Paul of Aegina. In their testimonies, one can find descriptions of aconite, its influence on the human body (and animals), and remedies for affected people.
In contrast, there are few passages from these sources that inform the readers about the healing properties of aconite. According to these fragments, carefully administered, aconite could be helpful in some therapies, but its use was extremely hazardous, as even a small part of the plant could kill a man.
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References
Aetii Amideni libri medicinales I–VIII, ed. A. Olivieri, Lipsiae–Berolini 1935–1950 [= Corpus Medicorum Graecorum, 8].
Google Scholar
Andocides, Orationes, ed. F. Blass, C. Fuhr, Stutgardiae 1966.
Google Scholar
Appendix Eclogae, [in:] Fontes Minores III, ed. L. Burgmann, S. Troianos, Frankfurt am Main 1974.
Google Scholar
Athenaeus, The Learned Banqueters, vol. I–VIII, ed. S. Douglas Olson, Cambridge Mass. 2006–2012 [= Loeb Classical Library], https://doi.org/10.4159/DLCL.atheneus_grammarian-learned_banqueters.2007
Google Scholar
DOI: https://doi.org/10.4159/DLCL.atheneus_grammarian-learned_banqueters.2007
Ausonius, Technopaegnion, [in:] Ausonius, vol. I, trans. H. G.E. White, Cambridge Mass. 1919 [= Loeb Classical Library, 96], https://doi.org/10.4159/DLCL.ausonius-technopaegnion.1919
Google Scholar
DOI: https://doi.org/10.4159/DLCL.ausonius-technopaegnion.1919
Basilica, vol. I–VIII, ed. H. J. Scheltema, N. van der Wal, Groningen 1955–1988.
Google Scholar
The Digest of Justinian, vol. IV, ed. T. Mommsen, P. Krueger, trans. A. Watson, Philadelphia 1985.
Google Scholar
Digesta Iustiniani Augusti, rec. T. Mommsen, Berolini 1870.
Google Scholar
Diogenes Laertius, Vitae philosophorum, vol. I, ed. M. Marcovich, Stuttgart–Leipzig 1999 [= Bibliotheca scriptorum Graecorum et Romanorum Teubneriana].
Google Scholar
Dioscorides, De materia medica: being an Herbal with Many Other Medicinal Materials. Written in Greek in the First Century of the Common Era, ed., trans. T. A. Osbaldeston, R. P.A. Wood, Johannesburg 2000.
Google Scholar
Dioscórides, Plantas y remedios medicinales, vol. IV–V, trans. M. G. Valdés, Madrid 1998.
Google Scholar
Galeni De antidotis libri II, [in:] Claudii Galeni opera omnia, vol. XIV, ed. C. G. Kühn, Lipsiae 1827.
Google Scholar
Galeni De compositione medicamentorum secundum locos, [in:] Claudii Galeni opera omnia, vol. XII–XIII, ed. C. G. Kühn, Lipsiae 1826–1827.
Google Scholar
Galeni De simplicium medicamentorum temperamentis ac facultatibus libri XI, [in:] Claudii Galeni opera omnia, vol. XI–XII, ed. C. G. Kühn, Lipsiae 1826–1827.
Google Scholar
Galeni In Hippocratis sextum librum epidemiarum commentaria I–VI, ed. E. Wenkebach, Leipzig 1940.
Google Scholar
Juvenal, Satirae, [in:] Juvenal and Persius, ed. S. Morton Braund, Cambridge Mass. 2004 [= Loeb Classical Library, 91], https://doi.org/10.4159/DLCL.juvenal-satires.2004
Google Scholar
DOI: https://doi.org/10.4159/DLCL.juvenal-satires.2004
Macrobius, Saturnalia, vol. I–III, ed. R. A. Kaster, Cambridge Mass. 2011 [= Loeb Classical Library, 510–512], https://doi.org/10.4159/DLCL.macrobius-saturnalia.2011
Google Scholar
DOI: https://doi.org/10.4159/DLCL.macrobius-saturnalia.2011
Nicandre, Les alexipharmaques, [in:] Nicandre, Oeuvres, vol. II, trans. J.-M. Jacques, Paris 2002.
Google Scholar
Nicandre, Les alexipharmaques, [in:] Nicandre, Oeuvres, vol. III, trans. J.-M. Jacques, Paris 2007.
Google Scholar
Nomocanon, [in:] Collectio Tripartita: Justinian on Religious and Ecclesiastical Affairs, ed. B. H. Stolte, N. van der Wal, Groningen 1994.
Google Scholar
Oribasii collectionum medicarum reliquiae, vol. I–IV, ed. I. Raeder, Lipsiae–Berolini 1928–1933 [= Corpus Medicorum Graecorum].
Google Scholar
Oribasii eclogae medicamentorum, [in:] Oribasii Collectionum medicarum reliquiae, vol. IV, Libri XLIX–L, libri incerti, eclogae medicamentorum, ed. J. Raeder, Leipzig–Berlin 1933 [= Corpus Medicorum Graecorum].
Google Scholar
Ovid, Metamorphoses. Books 1–8, trans. F. J. Miller, rev. G. P. Goold, Cambridge Mass. 1977 [= Loeb Classical Library].
Google Scholar
Paulus Aegineta, vol. I–II, ed. I. L. Heiberg, Lipsiae–Berolini 1921–1924.
Google Scholar
Pedanii Dioscuridis Anazarbei de materia medica libri V, vol. I–III, ed. M. Wellmann, Berolini 1906–1914.
Google Scholar
Pedanius Dioscorides of Anazarbus, De materia medica, trans. L. Y. Beck, Hildesheim 2020.
Google Scholar
Pliny the Elder, Natural History, vol. I–IX, trans. H. Rackham, W. H.S. Jones, D. E. Eichholz, Cambridge Mass. 1938–1963 [= Loeb Classical Library], https://doi.org/10.4159/DLCL.pliny_elder-natural_history.1938
Google Scholar
DOI: https://doi.org/10.4159/DLCL.pliny_elder-natural_history.1938
Plutarch, Crassus, [in:] Plutarch, Lives, vol. III, trans. B. Perrin, Cambridge Mass. 1916 [= Loeb Classical Library, 65].
Google Scholar
Plutarch, Demetrius, [in:] Plutarch, Lives, vol. IX, trans. B. Perrin, Cambridge Mass. 1920 [= Loeb Classical Library, 101].
Google Scholar
Prochiron Auctum, ed. P. Zepos, Athens 1931.
Google Scholar
Prochiron Legum vel Prochiron Calabriae, ed. F. Brandileone, V. Puntoni, Roma 1895.
Google Scholar
Scribonio Largo, Ricette mediche, trans. S. Sconocchia, Berlin 2020 [= Corpus medicorum Latinorum].
Google Scholar
Servii Grammatici in Vergili Bucolica et Georgica commentarii, rec. G. Thilo, Lipsiae 1887.
Google Scholar
Strabonis geographica, vol. I–III, ed. A. Meineke, Graz 1969.
Google Scholar
Synopsis basilicorum sive synopsis major, ed. P. Zepos, Athens 1931.
Google Scholar
Théophraste, Recherches sur les plantes, vol. V, Livre IX, trans. S. Amigues, Paris 2006.
Google Scholar
Theophrastus, Enquiry into Plants, [in:] Theophrastus, Enquiry into Plants and Minor Works, ed. A. Hort, Cambridge Mass. 1926.
Google Scholar
Amigues S., Commentaire, [in:] Théophraste, Recherches sur les plantes, vol. V, Livre IX, trans. S. Amigues, Paris 2006, p. 65–242.
Google Scholar
Been A., Aconitum: Genus of Powerful and Sensational Plants, “Pharmacy in History” 34.1, 1992, p. 35–39.
Google Scholar
Chan T. Y.K., Aconite Poisoning, “Clinical Toxicology” 47, 2009, p. 279–285, https://doi.org/10.1080/15563650902904407
Google Scholar
DOI: https://doi.org/10.1080/15563650902904407
Cilliers L., Retief F., Poisons, Poisoners, and Poisoning in Ancient Rome, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 127–137, https://doi.org/10.1016/B978-0-12-800045-8.00013-7
Google Scholar
DOI: https://doi.org/10.1016/B978-0-12-800045-8.00013-7
Deichmann W. B., Henschler D., Holmstedt B., Keil G., What is there that is not Poison? A Study of the Third Defense by Paracelsus, “Archives of Toxicology” 58, 1986, p. 207–213, https://doi.org/10.1007/BF00297107
Google Scholar
DOI: https://doi.org/10.1007/BF00297107
Diccionario griego-español, vol. I, ed. F. R. Adrados, Madrid 1989.
Google Scholar
Dybała J., Kokoszko M., Lecznicze działanie olei roślinnych na podstawie De materia medica Dioskuridesa, [in:] Lek roślinny, vol. VI, red. B. Płonka-Syroka, A. Syroka, Wrocław 2017, p. 81–93.
Google Scholar
Fausti D., La botanica medica di età imperiale. Piante narcotiche dal quarto libro di Dioscoride, [in:] Περὶ φυτῶν Trattati greci di botanica in Occidente e in Oriente, ed. M. F. Ferrini, G. Giglioni, Macerata 2020, p. 43–73.
Google Scholar
Jacques J.-M., Notice, [in:] Nicandre, Oeuvres, vol. II, trans. J.-M. Jacques, Paris 2002.
Google Scholar
Jauregui M. G., The Biological Assay of Aconite, “Journal of the American Pharmaceutical Association” 16.11, 1927, p. 1045–1052, https://doi.org/10.1002/jps.3080161106
Google Scholar
DOI: https://doi.org/10.1002/jps.3080161106
Jones-Lewis M., Pharmacy, [in:] A Companion to Science, Technology, and Medicine in Ancient Greece and Rome, vol. I, ed. G. L. Irby, Malden–Oxford 2016 [= Blackwell Companions to the Ancient World], p. 402–417, https://doi.org/10.1002/9781118373057.ch25
Google Scholar
DOI: https://doi.org/10.1002/9781118373057.ch25
Kaufman D. B., Poisons and Poisoning among the Romans, “Classical Philology” 27.2, 1932, p. 156–167, https://doi.org/10.1086/361458
Google Scholar
DOI: https://doi.org/10.1086/361458
Kokoszko M., Jagusiak K., Galen on Wine, or Some Traces of Preference, “Piotrkowskie Zeszyty Historyczne” 2020, special issue, p. 9–28.
Google Scholar
Laskaris J., Metals in Medicine: from Telephus to Galen, [in:] Popular Medicine in Graeco-Roman Antiquity: Explorations, ed. W. V. Harris, Leiden–Boston 2016 [= Columbia Studies in the Classical Tradition, 42], p. 147–160, https://doi.org/10.1163/9789004326040_007
Google Scholar
DOI: https://doi.org/10.1163/9789004326040_007
Lewkowicz-Mosiej T., Rośliny lecznicze, Warszawa 2012.
Google Scholar
Liddell H. G., Scott R., Jones H. S. et al., A Greek-English Lexicon, 9Oxford 1996.
Google Scholar
Mayor A., Mithridates of Pontus and his Universal Antidote, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 21–34, https://doi.org/10.1016/B978-0-12-800045-8.00004-6
Google Scholar
DOI: https://doi.org/10.1016/B978-0-12-800045-8.00004-6
Moritz F., Compagnon P., Guery Kaliszczak I., Kaliszczak Y., Caliskan V., Girault C., Severe Acute Poisoning with Homemade Aconitum napellus Capsules: Toxicokinetic and Clinical Data, “Clinical Toxicology” 43, 2005, p. 873–876, https://doi.org/10.1080/15563650500357594
Google Scholar
DOI: https://doi.org/10.1080/15563650500357594
Nadlewska A., Ładny J. R., Wojewódzka-Żelezniakowicz M., Czaban S. L., Kosierkiewicz W., Szymańska A., Łukasik-Głębocka M., Naskręt M., Górny J., Trucizny – definicja, rodzaje, mechanizm działania, “Postępy Nauk Medycznych” 9, 2010, p. 704–708.
Google Scholar
Nepovimova E., Kuca K., The History of Poisoning: from Ancient Times until Modern Era, “Archives of Toxicology” 93, 2019, p. 11–24, https://doi.org/10.1007/s00204-018-2290-0
Google Scholar
DOI: https://doi.org/10.1007/s00204-018-2290-0
Puri H. S., Uses of Aconites, “Journal d’agriculture tropicale et de botanique appliquée” 21.7, 1974, p. 239–246, https://doi.org/10.3406/jatba.1974.3168
Google Scholar
DOI: https://doi.org/10.3406/jatba.1974.3168
Riddle J. M., Dioscorides on Pharmacy and Medicine, Austin 1985, https://doi.org/10.7560/715448
Google Scholar
DOI: https://doi.org/10.7560/715448
Scarborough J., Drugs and Medicines in the Roman World, “Expedition” 38.2, 1996, p. 38–51.
Google Scholar
DOI: https://doi.org/10.2165/00003495-199600511-00008
Scarborough J., Drugs for an Emperor, “Amphora. A Publication of the American Philological Association” 3.1, 2004, p. 4–5, 17.
Google Scholar
Scarborough J., Herbs of the Field and Herbs of the Garden in Byzantine Medicinal Pharmacy, [in:] Byzantine Garden Culture, ed. A. Littlewood, H. Maguire, J. Wolschke-Bulmahn, Washington DC 2002, p. 177–188.
Google Scholar
Scarborough J., Theophrastus on Herbals and Herbal Remedies, “Journal of the History of Biology” 11.2, 1978, p. 353–385, https://doi.org/10.1007/BF00389304
Google Scholar
DOI: https://doi.org/10.1007/BF00389304
Shoaib A., Siddiqui H. H., Dixit R. K., Siddiqui S., Deen B., Khan A., Alrokayan S. H., Khan H. A., Ahmad P., Neuroprotective Effects of Dried Tubers of Aconitum napellus, “Plants” 9.3, 2020, art. 356, https://doi.org/10.3390/plants9030356
Google Scholar
DOI: https://doi.org/10.3390/plants9030356
Singh M. K., Vinod M., Iyer S. K., Khare G., Sharwan G., Larokar Y. K., Aconite: a Pharmacological Update, “International Journal of Research in Pharmaceutical Sciences” 3.2, 2012, p. 242–246.
Google Scholar
Skaltsa H., Philianos S., Papaphilippou G., L’aconit chez Nicandre et de nos jours, “Revue d’histoire de la pharmacie” 85.316, 1997, p. 405–410, https://doi.org/10.3406/pharm.1997.4893
Google Scholar
DOI: https://doi.org/10.3406/pharm.1997.4893
Szweykowska A., Szweykowski J., Botanika. Systematyka, vol. II, Warszawa 2012.
Google Scholar
Tai C.-J., El-Shazly M., Wu T.-Y., Lee K.-T., Csupor D., Hohmann J., Chang F.-R., Wu Y.-C., Clinical Aspects of Aconitum Preparations, “Planta Medica” 81, 2015, p. 1017–1028, https://doi.org/10.1055/s-0035-1546183
Google Scholar
DOI: https://doi.org/10.1055/s-0035-1546183
Takacs M., Frass M., Walderf G., Fibert P., Rottensteiner M., Glück W., Lechleitner P., Oberbaum M., Leisseri I., Chandak K., Panhofer P., Weiermayer P., Adjunctive Homeopathic Treatment of Hospitalized COVID-19 Patients (COVIHOM): A Retrospective Case Series, “Complementary Therapies in Clinical Practice” 44, 2021, p. 1–11, https://doi.org/10.1016/j.ctcp.2021.101415
Google Scholar
DOI: https://doi.org/10.1016/j.ctcp.2021.101415
Totelin L., Botanizing Rulers and their Herbal Subjects: Plants and Political Power in Greek and Roman Literature, “Phoenix” 66.1–2, 2012, p. 122–144, https://doi.org/10.1353/phx.2012.0013
Google Scholar
DOI: https://doi.org/10.1353/phx.2012.0013
Touwaide A., Murder, Execution, and Suicide in Ancient Greece and Rome, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. II, ed. P. Wexler, Amsterdam 2015, p. 1–8, https://doi.org/10.1016/B978-0-12-801506-3.00001-7
Google Scholar
DOI: https://doi.org/10.1016/B978-0-12-801506-3.00001-7
Tsoucalas G., Sgantzos M., The Death of Cleopatra: Suicide by Snakebite or Poisoned by her Enemies?, [in:] History of Toxicology and Environmental Health. Toxicology in Antiquity, vol. I, ed. P. Wexler, Amsterdam 2014, p. 11–20, https://doi.org/10.1016/B978-0-12-800045-8.00002-2
Google Scholar
DOI: https://doi.org/10.1016/B978-0-12-800045-8.00002-2
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