Morphology of dentition in Polish children with trisomy 21 (Down syndrome)
DOI:
https://doi.org/10.2478/v10044-010-0001-4Keywords:
metric dental traits, non-metric dental traits, odontologyAbstract
This paper compares the dimensions and non-metric dental traits between Down syndrome patients (DS) and a control group. A total of 1,210 teeth of subjects with Down syndrome (diagnosed as regular trisomy 21 type) were analyzed. The mesiodistal (MD) and labiolingual or buccolingual (BL) diameters of each dental crown were measured, and the selected non-metric dental traits evaluated. The teeth of male and female DS patients were found to have lower values of both measurements compared to controls (excepting for the mesiodistal diameter of the lower mandibular premolar both in males and females). Sexual dimorphism of dental crown dimensions characteristic of contemporary human populations (the highest M-F difference was lower than 6%) was also observed: boys' teeth, particularly canines, are bigger than girls' (2.33 on average). Disorders in maxillary tooth alignment and the faint shoveling of upper central incisors (grade 1 according to ASU scale) were noted significantly more often among Down syndrome patients, but descriptive features correlating with dental crown size were observed more rarely (e.g., the distal accessory ridge on the upper canine and tuberculum Carabelli on the first molar).
Downloads
References
Barden H. S., 1980a, Dental asymmetry and mental retardation: a comparison of subjects with mental retardation resulting from prenatal or postnatal influences, J. Ment. Defic. Res., 24, 107-13
View in Google Scholar
Barden H. S., 1980b, Fluctuating dental asymmetry: a measure of developmental instability in Down Syndrome, Am. J. Phys. Anthropol., 52, 169-73
View in Google Scholar
Barden H. S., 1980c, Mesiodistal crown size dimensions of permanent and deciduous teeth in Down syndrome, Hum. Biol., 52, 247-53
View in Google Scholar
Bell E., G. Townsend, D. Wilson, 2001, Effect of Down syndrome on the dimensions of dental crowns and tissues, Am. J. Hum. Biol., 13, 690-98
View in Google Scholar
Bromhan N. R., J. M. Woodhouse, M. Cregg, E. Webb, W. T. Fraser, 2002, Heart defects and ocular anomalies in children with Down's syndrome, Br. J. Ophthalmol., 86, 1367-68
View in Google Scholar
Brown T., C. G. Townsend, 1984, Size and shape of mandibular first molars in Down syndrome, Ann. Hum. Biol., 11, 281-90
View in Google Scholar
Brugge K. L., G. L. Grove, P. Clopton, M. J. Grove, D. J. Piacquadio, 1993, Evidence for accelerated skin wrinkling among developmentally delayed individuals with Down's syndrome, Mech. Ageing Dev., 70, 213-25
View in Google Scholar
Cosgrave M. P., J. Tyrrell, M. McCarron, M. Gill, B. A. Lawlor, 1999, Age at onset of dementia and age of menopause in women with Down syndrome, J. Intellect. Disabil. Res., 43, 461-65
View in Google Scholar
Delabar J. M., D. Theophile, Z. Rahmani, Z. Chettouh, J. L. Blouin, et al., 1993, Molecular mapping of twenty-four features of Down syndrome on chromosome 21, Europ. J. Hum. Genet., 1, 114-24
View in Google Scholar
Fisher-Brandies H., 1989, The time of eruption of the milk teeth in Down's disease, Fortschr. Kieferorthop., 50, 144-51
View in Google Scholar
Goździcka-Józefiak M., M. Bobowicz, H. Kędzia, 2001, Podział chorób genetycznych, [in:] Genetyka molekularna i biochemia wybranych chorób u ludzi, M. Goździcka-Józefiak, M. Bobowicz, H. Kędzia (eds.), Wyd. UAM, Poznań, pp. 63-69
View in Google Scholar
Hattab F. N., S. al-Khateeb, I. Sultan, 1996, Mesiodistal crown diameters of permanent teeth in Jordanians, Arch. Oral. Biol., 41, 641-45
View in Google Scholar
Hillson S., 1996, Dental anthropology, 2nd Edition, Cambridge Univ. Press, Cambridge, pp. 68-105
View in Google Scholar
Hitzler J. K., J. Cheung, Y. Li, S. W. Scherer, A. Zipursky, 2003, GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome, Blood, 101, 4301-04
View in Google Scholar
Jara L., A. Ondarza, R. Blanco, C. Valenzuela, 1993, The sequence of eruption of the permanent dentition in Chilean sample with Down's syndrome, Arch. Oral. Biol., 38, 85-89
View in Google Scholar
Kaczmarek M., J. Piontek, A. Malinowski, 1988, Dental discriminant sexing of human cremated remains, Prz. Antropol., 52, 203-8
View in Google Scholar
Keinan D., P. Smith, U. Zilberman, 2006, Microstructure and chemical composition of primary teeth in children with Down syndrome and cerebral palsy, Arch. Oral Biol., 51, 836-43
View in Google Scholar
Korenberg J. R., X. N. Chen, R. Schipper, Z. Sun, R. Gonsky, et al., 1994, Down syndrome phenotypes: the consequences of chromosomal imbalance, Proc. Natl. Acad. Sci. USA, 91, 4997-5001
View in Google Scholar
Madan V., J. Wiliams, J. T. Lear, 2006, Dermatological manifestations of Down's syndrome, Clin. Exp. Dermat., 31, 623-29
View in Google Scholar
Mikkelsen M., 1982, Parental origin of the extra chromosome in Down's syndrome, J. Ment. Defic. Res., 26, 143-51
View in Google Scholar
Mitchell R. B., E. Call, J. Kelly, 2003, Ear, nose and throat disorders in children with Down syndrome, Laryngoscope, 113, 259-63
View in Google Scholar
Mittwoch W., 1972, Mongolism and sex: A common problem of cell proliferation?, J. Med. Genet., 9, 92-95
View in Google Scholar
Mizoguchi Y., 1985, Shovelling: A statistical analysis of its morphology, Tokyo Univ. Mus. Bull., 26
View in Google Scholar
Nakamura E., S. Tanaka, 1998, Biological ages of adult men and women with Down's syndrome and its changes with ageing, Mech. Ageing Dev., 105, 89-103
View in Google Scholar
Nery E. B., B. S. Kraub, M. Croup, 1975, Dental organ formation: a chronological and topographic sequence, J. Dent. Child., 42, 467-73
View in Google Scholar
Paton G. R., M. F. Silver, A. C. Allison, 1974, Comparison of cell cycle time in normal and trisomic cell, Humangenetic, 23, 173-82
View in Google Scholar
Peretz B., J. Shapira, H. Farbstein, E. Arieli, P. Smith, 1996, Modification of tooth size and shape in Down's syndrome, J. Anat., 188, 167-72
View in Google Scholar
Peretz B., J. Shapira, H. Farbstein, E. Arieli, P. Smith, 1998, Modified cuspal relationships of mandibular molar teeth in children with Down's syndrome, J. Anat., 193, 529-33
View in Google Scholar
Prahl-Andersen B, J. Oerlemans, 1976, Characteristics of permanent teeth in persons with trisomy G, J. Dent. Res., 55, 633-38
View in Google Scholar
Rosiński F. M., 1992, Charakterystyka genetyczna, morfologiczna i środowiskowa pacjentów z zespołem Downa, [in:] Biologia populacji ludzkich współczesnych i pradziejowych, F. Rożnowski (ed.), WSP Słupsk, pp. 397-408
View in Google Scholar
Royston M. C., J. E. McKenzie, S. M. Gentleman, J. G. Sheng, D. M. Mann, et al., 1999, Overexpression of s100beta in Down's syndrome: correlation with patient age and with beta-amyloid deposition, Neuropathol. Appl. Neurobiol., 25, 387-93
View in Google Scholar
Scott G. R., G. C. Turner, 1997, The anthropology of modern human teeth, Cambridge Univ. Press, Cambridge, UK, pp. 74-164
View in Google Scholar
Townsend G. C., 1983a, Fluctuating dental asymmetry in Down's syndrome, Aust. Dent. J., 28, 39-44
View in Google Scholar
Townsend G. C., 1983b, Tooth size in children and young adults with trisomy 21 (Down) syndrome, Arch. Oral. Biol., 28, 159-66
View in Google Scholar
Townsend G. C., 1986, Dental crown variants in children and young adults with Down syndrome, Acta Odontol. Pediatr., 7, 35-39
View in Google Scholar
Townsend G. C., L. Alvesalo, B. L. Jensen, M. Kari, 1988, Patterns of tooth size in chromosomal aneuploidies, [in:] Teeth revisited: Proceedings of the VIIth International Symposium on Dental Morphology, D. E. Russell, J. P. Santoro, D. Sigogneau-Russel (eds.), Science de la Terre, 53, Paris, pp. 25-45
View in Google Scholar
Townsend G. C., R. H. Brown, 1983, Tooth morphology in Down's syndrome: Evidence for retardation in growth, J. Ment. Defic. Res., 27, 159-69
View in Google Scholar
Turner II C. G., C. R. Nichol, G. R. Scott, 1991, Scoring procedures for key morphological traits of the permanent dentition: the Arizona State University Dental Anthropology System, [in:] Advances in dental anthropology, M. A. Kelley, C. S. Larsen (eds.), Wiley-Liss, New York, pp. 13-31
View in Google Scholar
Türp J. C., K. W. Alt, 1998, Anatomy and morphology of human teeth, [in:] Dental Anthropology. Fundamentals, Limits, and Prospect, K. W. Alt, F. W. Rosing, M. Teschler-Nicola (eds.), Springer, Wien, pp. 71-94
View in Google Scholar
Ulijaszek S. J., J. A. Lourie, 1994, Intra- and inter-observer error in anthropometric measurement, [in:] Anthropometry: the individual and the population, S. J. Ulijaszek, C. G. N. Mascie-Taylor (eds.), Cambridge Univ. Press, Cambridge, pp. 30-55
View in Google Scholar
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
