The influence of selected environmental factors on the time of natural menopause in women living in the Małopolskie voivodeship
DOI:
https://doi.org/10.2478/v10044-012-0011-5Keywords:
natural menopause, environmental factors, cigarette smoking, alcohol intakeAbstract
The main objective of the study is to determine which of the chosen environmental factors and selected groups of such factors alter the time of natural menopause in women living in the Małopolska region. Two hundred and thirty two women aged over 40 years were investigated in a cross-sectional survey in Cracow and the surrounding area. Among them 165 women who had undergone natural menopause and had their last bleeding at least 12 month prior to the interview were chosen. To estimate the age at menopause, a retrospective method was used. Univariate and multivariate methods were employed to estimate association of age at natural menopause with factors of interest. Mean age at natural menopause was 50.32 years (SD=3.82). Among biological and socio-economic factors, only the length of the reproductive period (H=106.07; p=0.000) and the age at the time of the first birth (R=0.18; p=0.020) turned out to be associated with the age at natural menopause in the studied group. The length of the smoking period (R=–0.17; p=0.031), the amount (F=3.25; p=0.04) and frequency of alcohol consumed (H=6.95; p=0.031) were the environmental factors related to the time of menopause. Women who drank more and smoked over longer period of time were likely to experience menopause earlier than their less drinking and shorter smoked counterparts. Three factors taken together, frequency of smoking, alcoholic intake and the age the tobacco addiction started (F=3.87; p=0.050), as well as the consumption of strong alcoholic drinks and the early start of tobacco addiction (F=2.85; p=0.026) were significantly related to the occurrence of natural menopause.
Downloads
References
Bradbury J. 2001. Mechanism found for smoking-induced early menopause. Lancet 358:215.
View in Google Scholar
Carda SN, Bilge SA, Ozturk TN, Oya G, Ece O, et al. 1998. The menopausal age, related factors and climacteric symptoms in Turkish women. Maturitas 30:37–40.
View in Google Scholar
Cassou B, Derriennic F, Monfort C, Dell’Accio P, Touranchet A. 1997. Risk factors of early menopause in two generations of gainfully employed French women. Maturitas 26:165–76.
View in Google Scholar
Cramer DW, Harlow LB, Huijuan X, Fraer C, Barbieri R. 1996. Cross-sectional and case-controlled analyses of the association between smoking and early menopause. Maturitas 22:79–87.
View in Google Scholar
Dorgan JF, Baer DJ, Albert PS. 2001. Serum hormones and the alcohol-breast cancer association in postmenopausal women. J Natl Cancer Inst 93:710–15.
View in Google Scholar
Emanuele MA, Wezeman F, Emanuele NV. 2002. Alcohol’s Effects on Female Reproductive Function. Alc Hlth Res World 26:274–81.
View in Google Scholar
Gavaler JS, Rosenblum E. 1987. Exposure-dependent effects of ethanol on serum estradiol and uterus mass in sexually mature oophorectomized rats: A model for bilaterally ovariectomized-postmenopausal women. J Stud Alcohol 48:295–303.
View in Google Scholar
Gavaler JS, Van Thiel DH. 1992. The association between moderate alcoholic beverage consumption and serum estradiol and testosterone levels in normal postmenopausal women: Relationship to the literature. Alcohol Clin Exp Res 16:87–92.
View in Google Scholar
Johannes C, Crafford S, Mckin LS. 1997. The effect of alcohol and estrogen replacement therapy (ERT) on estrogen levels in postmenopausal women. Am J Epidemiol 145:S1.
View in Google Scholar
Johansson Ch., Mellström D. 1996. An earlier fracture as a risk factor for new fracture and it association with smoking and menopausal age in women. Maturitas 24:97–104.
View in Google Scholar
Kaczmarek M. 2007. The timing of natural menopause in Poland and associated factors. Maturitas 57:139–53.
View in Google Scholar
Kinney A, Kline J, Levin B. 2006. Alcohol, caffeine and smoking in relation to age at menopause. Maturitas 54:27–38.
View in Google Scholar
Mattison DR, Thorgeisson SS. 1978. Smoking and industrial pollution, and their effects on menopause and ovarian cancer. Lancet 1:187–88.
View in Google Scholar
Mendelson JH, Mello NK. 1988. Chronic alcohol effects on anterior pituitary and ovarian hormones in healthy women. J Pharmacol Exp Ther 245:407–12.
View in Google Scholar
Meschia M, Pansini F, Modena AB, de Aloysio D, Gambaccini M, et al. 2000. Detrminants of age at menopause in Italy: results from a large cross-sectional study. Maturitas 34:119–25.
View in Google Scholar
Nagata C, Takatsuka N, Inaba S, Kawakami N, Shimizu H. 1998. Association of diet and lifestyle with onset of menopause in Japanese women. Maturitas 29:105–13.
View in Google Scholar
Pakarinen M, Raitanen J, Kaaja N, Luoto R. 2010. Secular trend in the menopausal age in Finland 1997–2007 in correlation with socioeconomic, reproductive and lifestyle factors. Maturitas 66:417–22.
View in Google Scholar
Parente RC, Faerstein E, Celeste RK, Werneck GL. 2008. The relationship between smoking and age at the menopause: A systematic review. Maturitas 61:287–98.
View in Google Scholar
Pawlińska-Chmara R, Szwed A. 2008. Cigarette smoking and age at natural menopause of women in Poland. Internet J Biol Anthropol 2(1) doi: 10.5580/4c7.
View in Google Scholar
Parazzini F, Progetto Menopausa Italia Study Group. 2007. Determinants of age at menopause in women attending menopause clinics in Italy. Maturitas 56:280–87.
View in Google Scholar
Przychodni A. 2010. Menopauza w ujęciu biologicznym i społecznym. Kielce: Wydawnictwo Uniwersytetu Humanistyczno-Przyrodniczego Jana Kochanowskiego.
View in Google Scholar
Register CR, Cline M, Carol A, Shively CA. 2002. Health issues in postmenopausal women who drink. Alc Hlth Res World 26:99–307.
View in Google Scholar
Report of a WHO Scientific Group 1981. Research on the menopause. WHO Technical Report Series 670. Geneva: World Health Organization.
View in Google Scholar
Report of a WHO Scientific Group 1996. Research on the menopause in the 1990s. WHO Technical Report Series 866. Geneva: World Health Organization.
View in Google Scholar
Rodziewicz-Gruhn J. 1998. Genetyczne i środowiskowe uwarunkowania wieku menopauzy i długości okresu rozrodczego. Studies in Human Ecology 2:201–10.
View in Google Scholar
Spandorfer S. 1996. Cigarette smoking: its effects on the perimenopausal women. Primary Care Update for OB/GYNS 3:212.
View in Google Scholar
Stachoń A. 2007. Zróżnicowanie wieku menopauzy i przebiegu klimakterium mieszkanek Polski południowej w zależności od działania czynników biologicznych i społecznych, PhD dissertation. Kraków: Uniwersytet Jagielloński.
View in Google Scholar
Szwed A. 2001. Biologiczne i kulturowe uwarunkowania klimakterium u kobiet. Monografie Instytutu Antropologii 10. Poznan: UAM.
View in Google Scholar
Van Thiel DH, Gavaler JS, Lester R, Shreins RJ. 1978. Alcohol-induced ovarian failure in the rat. J Clin Invest 61:624–32.
View in Google Scholar
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.